Preparation of racemic 2,3-diaminobutane and the resolution of its (2S,3S) enantiomer

✍ Scribed by Mike G. Scaros; Peter K. Yonan; Scott A. Laneman; Peter N. Fernando

• Book ID: 104361178
• Publisher: Elsevier Science
• Year: 1997
• Tongue: English
• Weight: 344 KB
• Volume: 8
• Category: Article
• ISSN: 0957-4166
• DOI: 10.1016/s0957-4166(97)00156-0

✦ Synopsis

A three-step procedure for large scale preparation of pure racemic 2,3diaminobutane from relatively inexpensive meso 2,3-butanediol is described. Also, an efficient method for the resolution of (S,S) 2,3-diaminobutane from the racemic mixture in <95% ee has been developed.