𝔖 Bobbio Scriptorium
✦   LIBER   ✦

2,6-Piperidinediones, I. Synthesis of the Racemates and the Enantiomers of 3,3-Disubstituted 2,6-Piperidinediones

✍ Scribed by Joachim Knabe; Dirk Reischig


Publisher
John Wiley and Sons
Year
1984
Tongue
English
Weight
561 KB
Volume
317
Category
Article
ISSN
0365-6233

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Piperidinediones, III. Structure-Activit
✍ Joachim Knabe; Horst P. BΓΌch; Dirk Reischig πŸ“‚ Article πŸ“… 1984 πŸ› John Wiley and Sons 🌐 English βš– 255 KB πŸ‘ 2 views

Among the racemic 2.6-piperidinediones 1-6, compound 6 has the highest anesthetic activity. The enantiomers of 1, 2 , 4 and 5 possess different anesthetic potencies depending on the nature of the aliphatic side chain. The S(-)-enantiomen of the piperidinediones 2, 3 and 5 cause initial CNS stimulati

The fischer indolization of 4-acetonyl-2
✍ Mercedes Amat; Enric Sanfeliu; Joan Bosch πŸ“‚ Article πŸ“… 1989 πŸ› Elsevier Science 🌐 French βš– 567 KB

The PPA induced Fischer indolization of 4-acetonyl-2,6-piperidinediones 4 takes place both at the methylene and the methyl carbons, although the latter regioisomer (3) undergoes a further cyclization of the imide moiety upon the indole 3position followed by ring-opening of the resulting intermediate

Diastereoselective synthesis of 3,6-disu
✍ Thomas F. Anderson; Julian G. Knight; Kirill Tchabanenko πŸ“‚ Article πŸ“… 2003 πŸ› Elsevier Science 🌐 French βš– 162 KB

In a short sequence, 5-vinyloxazolidin-2-ones were converted into the 3,6-disubstituted 3,6-dihydropyridin-2-ones via Pd-catalysed carbonylation and enolate alkylation with high diastereoselectivity. Alkylation of 6-substituted N-methylpyridin-2ones gives stereoselectively the 3,6-anti diastereoisom