Preparation of methylcyclopentane-1-d1
✍ Scribed by Dan Fǎrcaşiu; Geraldine Drevon
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- French
- Weight
- 172 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0022-2135
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract A nine‐step preparation of 4‐iodo‐2‐methyl‐1‐butene‐1,1‐__d__~2~ (**9**) from 2‐methylbutyrolactone (**1**) is described.
The immunosuppressive macrolides ascomycin % 1 and FK 506 % 2 were stereoselectively deuteriated at C(32) using Curran's radical translocating method. Both AIBN and Et 3 B/O 2 were tested as radical initiator for the radical translocation/reduction step with Bu 3 SnD as reducing agent. Despite only
Die Verbindungen ( I ) gestatten die Darstellung kondensierter Heterocyclen. So entsteht z. B. durch mehrstiindiges Erliitzen von 2-Chlorindol-3-carbaldehyd ( I c ) in iiberschiissigem Formamid das 9H-Pyrimido\4,5-b]indol ( 2 ) (Fp = 7-35 bis 237°C) mit 80 ",; Ausbeute. Eingegangen am 14. Ohtober 19
## Abstract The ^1^H NMR spectral parameters of all eight 1,2‐diacetoxy‐3,4‐dimethylcyclopentanes and 1,2‐diacetoxy‐4‐__t__‐butyl‐3‐methylcyclopentanes are discussed.