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Preparation of high molecular weight radioiodinated alginic acid

✍ Scribed by P. Orlando; L. Binaglia; A. De Feo; R. Trevisi; C. Melodia; R. Trenta

Publisher
John Wiley and Sons
Year
1994
Tongue
French
Weight
233 KB
Volume
34
Category
Article
ISSN
0022-2135

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✦ Synopsis

Abstract

A simple procedure is described for preparing^125^I‐labelled alginic acid. The reducing terminal of alginic acid is derivatized with tyramine through the formation of Schiff base which is subsequently reduced with sodium cyanoborohydride. By radioiodination of the aromatic ring introduced,^125^I‐labelled alginic acid was obtained with high specific activity.

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