Preparation of dihydrotetrazolo[1,5-a]pyrimidine derivatives from Biginelli 3,4-dihydropyrimidine-2-thiones
β Scribed by Hashim, Jamshed; Arshad, Nuzhat; Khan, Ijaz; Nisar, Sonia; Ali, Basharat; Iqbal Choudhary, M.
- Book ID
- 126705508
- Publisher
- Elsevier Science
- Year
- 2014
- Tongue
- French
- Weight
- 648 KB
- Volume
- 70
- Category
- Article
- ISSN
- 0040-4020
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π SIMILAR VOLUMES
We report herein the use of triphenylphosphine (TPP) as a new catalyst for the one-pot Biginelli reaction coupling of b-ketoesters, aldehydes and urea (or thiourea) to afford the corresponding dihydropyrimidinones/thiones.
## Abstract An efficient and convenient method for thiazolo[3,2βa]pyrimidines from cyclization reaction of dihydropyrimidineβthiones with Ξ±βbromoacetone in aqueous media is described. Β© 2008 Wiley Periodicals, Inc. Heteroatom Chem 19:149β153, 2008; Published online in Wiley InterScience (www.inters