Efficient synthesis of 5H-thiazolo[3,2-a]pyrimidines from reactions of 3,4-dihydropyrimidine-thiones with α-bromoacetone in aqueous media
✍ Scribed by Zheng-Jun Quan; Zhang Zhang; Jun-Ke Wang; Xi-Cun Wang; Ya-Juan Liu; Peng-Yan Ji
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 134 KB
- Volume
- 19
- Category
- Article
- ISSN
- 1042-7163
- DOI
- 10.1002/hc.20386
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
An efficient and convenient method for thiazolo[3,2‐a]pyrimidines from cyclization reaction of dihydropyrimidine‐thiones with α‐bromoacetone in aqueous media is described. © 2008 Wiley Periodicals, Inc. Heteroatom Chem 19:149–153, 2008; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.20386
📜 SIMILAR VOLUMES
## Abstract magnified image A series of new hexahydropyrido[2,3‐__d__]pyrimidine derivatives 3 were synthesized by the cyclocondensation reaction of (arylmethylidene)pyruvic acids (=(3__E__)‐4‐aryl‐2‐oxobut‐3‐enoic acids) 1 and 6‐aminouracils (=6‐aminopyrimidine‐2,4(1__H__,3__H__)‐diones) 2 in H~2