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Preparation of bis-/2-chloroethyl-1,2-3H/methylamine hydrochloride

✍ Scribed by J. Filip

Publisher: John Wiley and Sons
Year: 1966
Tongue: French
Weight: 232 KB
Volume: 2
Category: Article
ISSN: 0022-2135
DOI: 10.1002/jlcr.2590020308

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✦ Synopsis

Bis-(2-~hloroethy1-1,2-~H)methylamine hydrochloride was prepared, The starting product was a ~e t y l e n e -l , 2 -~H which was selectively hydrogenated to ethylene-1 ,2-3H. It was observed that on reduction with chromium ( I I ) chloride solution in dilute hydrochloric acid the isotopic exchange with ~cetylene-1,2-~H is negligible. Ethylene was converted to ethyleneoxide-1,23H by the usual method.

EthyEeneo~ide-l,2-~H can be used for synthesis of several labelled halogenalkylamines and as the starting compound for other syntheses.

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