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Preparation of [7,7-2H2] lithocholic acid

✍ Scribed by G. Phillipou; C. J. Seaborn; R. N. Butler

Publisher
John Wiley and Sons
Year
1981
Tongue
French
Weight
206 KB
Volume
18
Category
Article
ISSN
0022-2135

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✦ Synopsis

Abstract

Electrochemical deoxygenation of methyl 7‐keto‐lithocholate using deuterated reagents, followed by base hydrolysis is shown to give [7,7‐^2^H~2~] lithocholic acid in 60% overall yield and 86% ^2^H~2~ isotopic purity.

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