The preparation of dimethyl(7-2H3 2-oxoheptyl) phosphonate
✍ Scribed by Douglas F. Taber; Charles H. Lee
- Publisher
- John Wiley and Sons
- Year
- 1978
- Tongue
- French
- Weight
- 145 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0022-2135
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
Dimethyl (7‐^2^H~3~ 2‐oxoheptyl) phosphonate 4 has been prepared from ^2^H~3~ methyl iodide. The phosphonate should be a useful reagent for the synthesis of deuterium labelled prostaglandins and thromboxanes.
📜 SIMILAR VOLUMES
## Abstract Electrochemical deoxygenation of methyl 7‐keto‐lithocholate using deuterated reagents, followed by base hydrolysis is shown to give [7,7‐^2^H~2~] lithocholic acid in 60% overall yield and 86% ^2^H~2~ isotopic purity.
## Abstract magnified image 5‐Hydrazinoquinoline and 8‐hydrazinoquinoline were converted __via__ Fischer syntheses with 3‐methyl‐butan‐2‐one into pyrido‐indolenines 2,3,3‐trimethyl‐3__H__‐pyrrolo[2,3‐__f__]quinoline **7** and 2,3,3‐trimethyl‐3__H__‐pyrrolo[3,2‐__h__]quinoline **11**, respectively.