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Preparation of 7-Chloro-4-(2 piperidylmethyl-amino)-quinoline1

โœ Scribed by Norton, T; Benson, A; Seibert, R; Bergstrom, F


Book ID
126948537
Publisher
American Chemical Society
Year
1946
Tongue
English
Weight
221 KB
Volume
68
Category
Article
ISSN
0002-7863

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Preparation of 1-methyl-4-[4-(7-chloro-4
โœ Theodore S. T. Wang; Rashid A. Fawwaz; Ronald L. Van Heertum ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 292 KB ๐Ÿ‘ 1 views

1 -M e t h y l -4 -[ 4 -( 7 -c h l o r 0 -4 -q ~n i n o l y l -[ 3 -~~C 1amino)-benzoyllpiperazine (V) was prepared for pharmacokinetic and pharmacodynamic evaluation. The synthesis of V was accomplished first by a modified Claisen ester condensation reaction of diethyl-[2-14C]-malonate, triethyl or