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Synthesis of 7-Chloro-4-[1-methyl-(1-pyrrolidyl)-butylamino]-quinoline

โœ Scribed by Reitsema, Robert H.; Hunter, James H.


Book ID
126057855
Publisher
American Chemical Society
Year
1949
Tongue
English
Weight
248 KB
Volume
71
Category
Article
ISSN
0002-7863

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4-(4-Chloroยญphenyl)-1,7,7-triยญmethyl-1,2
โœ Tu, Shujiang ;Zhu, Xiaotong ;Zhang, Jinpeng ;Xu, Jianing ;Wang, Qian ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› International Union of Crystallography ๐ŸŒ English โš– 130 KB

The title compound, C 18 H 20 ClNO 2 , has been synthesized by the reaction of 4-chlorobenzaldehyde, Meldrum's acid, dimedone and CH 3 NH 3 Cl(NaOAc) in ethanol under microwave irradiation. The pyridone ring adopts a screw-boat conformation and the cyclohexenone ring an envelope conformation.