𝔖 Bobbio Scriptorium
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Preparation of 3-Spirocyclic Indolin-2-ones as Ligands for the ORL-1 Receptor.

✍ Scribed by Gilles C. Bignan; Kathleen Battista; Peter J. Connolly; Michael J. Orsini; Jingchun Liu; Steven A. Middleton; Allen B. Reitz


Publisher
John Wiley and Sons
Year
2006
Weight
11 KB
Volume
37
Category
Article
ISSN
0931-7597

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## Abstract Catalytic hydrogenation of 1‐aminocyclopropenecarboxylic acid under tritium gas afforded [2,3‐^3^H]1‐aminocyclopropanecarboxylic acid with specific activity 26 Ci/mmol, determined by a combination of ^1^H and ^3^H NMR. Pilot radioligand binding assays indicate this compound will be a us