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ChemInform Abstract: A Search for New 5-HT1A/5-HT2A Receptor Ligands. In vitro and in vivo Studies of 1-[ω-(4-Aryl-1-piperazinyl)alkyl]indolin-2(1H)-ones.

✍ Scribed by M. J. MOKROSZ; B. DUSZYNSKA; S. MISZTAL; A. KLODZINSKA; E. TATARCZYNSKA; E. CHOJNACKA-WOJCIK; M. DZIEDZICKA-WASYLESKA

Publisher
John Wiley and Sons
Year
2010
Weight
39 KB
Volume
30
Category
Article
ISSN
0931-7597

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📜 SIMILAR VOLUMES

Structure-Activity Relationship Studies
Structure-Activity Relationship Studies of CNS Agents, XV: N-[ω-(4-Aryl-1-piperazinyl)alkyl]-2-oxo-1,2,3,4-tetrahydroquinolines and -4-oxo-1,2,3,4-tetrahydropyrazino[1,2-a]indoles: New, Highly Potent 5-HT1A Ligands ωN-[ω-(4-Aryl-1-piperazinyl)alkyl]-2-oxo-1,2,3,4-tetrahydrochinoline und -4-oxo-1,2,3,4-tetrahydropyrazino-[1,2-a]indole: Neue starke 5-HT1A Liganden
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ChemInform Abstract: 1-[ω-(4-Arylpiperaz
ChemInform Abstract: 1-[ω-(4-Arylpiperazin-1-yl)alkyl] -3-diphenylmethylene-2,5-pyrrolidinediones as 5-HT1A Receptor Ligands: Study of the Steric Requirements of the Terminal Amide Fragment on 5-HT1A Affinity/Selectivity.
✍ M. L. LOPEZ-RODRIGUEZ; M. J. MORCILLO; T. K. ROVAT; E. FERNANDEZ; A. M. SANZ; L. 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 40 KB

## 1-[ω-(4-Arylpiperazin-1-yl)alkyl] -3-diphenylmethylene-2,5pyrrolidinediones as 5-HT 1A Receptor Ligands: Study of the Steric Requirements of the Terminal Amide Fragment on 5-HT 1A Affinity/Selectivity. -Two different methods are used to prepare the desired title compounds (IV) and (VII) which