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Preparation of 2,7-Diaminosubstituted-[1,2,4]triazolo[1,5- a ]pyrimidine-6-Carbonitriles by Solid-Phase Synthesis

✍ Scribed by Cavallaro, Cullen L.; Harikrishnan, Lalgudi S.; Chi, Feng; Dodd, Dharmpal; Purandare, Ashok

Book ID: 118023581
Publisher: American Chemical Society
Year: 2008
Tongue: English
Weight: 118 KB
Volume: 10
Category: Article
ISSN: 1520-4766
DOI: 10.1021/cc700161r

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## Abstract magnified image The 7‐aryl‐4,7‐dihydro[1,2,4]triazolo[1,5‐__a__]pyrimidines **1a**, **1b**, **1c** can undergo addition of hydrazine to the enamine double bond leading to hydrazine derivatives of tetrahydrotriazolopyrimidines **2a**, **2b**, **2c**; the process is usually accompanied by