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Three-component synthesis of some 2-amino-5-hydroxy-[1,2,4]triazolo[1,5-a]pyrimidine-6-carbonitriles and 2-(cyanoamino)-4-hydroxypyrimidine-5-carbonitriles

✍ Scribed by Reza Ranjbar-Karimi; Khalil Beiki-Shoraki; Asghar Amiri

Publisher: Springer Vienna
Year: 2010
Tongue: English
Weight: 891 KB
Volume: 141
Category: Article
ISSN: 0026-9247
DOI: 10.1007/s00706-010-0371-8

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## Abstract The synthesis of 6‐methylsulfanyl‐2,4‐dithioxo‐1,2,3,4‐tetrahydropyrimidine‐5‐carbonitrile **4** is described. Compound **4** was reacted with various alkylants. The reaction with chloroacetic acid derivatives results in the formation of thieno[2,3‐__d__]pyrimidines **8**. When methyl i