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Synthesis and Reactions of 6-Methylsulfanyl-2,4-dithioxo-1,2,3,4-tetrahydropyrimidin-5-carbonitrile .

โœ Scribed by Detlef Briel; Tanja Franz; Bodo Dobner


Publisher
John Wiley and Sons
Year
2003
Weight
264 KB
Volume
34
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Synthesis and Excha
โœ C. A. BATTY; M. K. MANTHEY; J. KIRK; M. MANTHEY; R. I. CHRISTOPHERSON; T. HAMBLE ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 35 KB ๐Ÿ‘ 2 views

Synthesis and Exchange Reactions of 5-Alkyl-2-oxo-6-thioxo-1,2,3,6-Tetrahydropyrimidine-4-carboxylic Acids. -The title compounds are prepared as potential dihydroorotase inhibitors. H/D-exchange studies establish a high tendency towards epimerization at C-5. No epimerization is observed under physi