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Synthesis of 5-Alkyl-1,3-bis [2-hydroxy-3- (6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-3-yl)propyl] -6-methyl-1,2,3,4-tetrahydropyrimidine-2,4-diones

✍ Scribed by V. P. Krivonogov; G. G. Kozlova; E. A. Belaya; G. A. Sivkova; L. V. Spirikhin; I. B. Abdrakhmanov; V. V. Plechev


Publisher
John Wiley and Sons
Year
2004
Weight
20 KB
Volume
35
Category
Article
ISSN
0931-7597

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Alkylation of 1-(3,4-Disubstituted Phenyl)-2-thioxo-1,2,5,6tetrahydropyrimidin-4(3H)-ones. -Alkylation of the title compounds (I), (VI), and (IX) results in the formation of S-and N-methylated derivatives. S-methylated products (III), (VII), and (X) are always the major products. In all cases, meth