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Synthesis of [1,2,4]triazolo[1,5-a]quinazolines from 7-methyl-5-phenyl-4,7-dihydro[1,2,4]triazolo[1,5-a]pyrimidine

✍ Scribed by Dmitrii Yu. Sidorenko; Valerii D. Orlov


Book ID
108209757
Publisher
Royal Society of Chemistry
Year
2010
Tongue
English
Weight
214 KB
Volume
20
Category
Article
ISSN
0959-9436

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Addition of hydrazine to 4,7-dihydro[1,2
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## Abstract magnified image The 7‐aryl‐4,7‐dihydro[1,2,4]triazolo[1,5‐__a__]pyrimidines **1a**, **1b**, **1c** can undergo addition of hydrazine to the enamine double bond leading to hydrazine derivatives of tetrahydrotriazolopyrimidines **2a**, **2b**, **2c**; the process is usually accompanied by

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The title compound, C 12 H 14 N 6 , was synthesized via cyclocondensation of 5-amino-1-guanyl-3-phenyl-1,2,4-triazole with acetone. Only one tautomeric form with an H atom at the triazine N atom was observed in the crystal structure. The compound crystallizes with two almost identical molecules in t

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7,7-Dimethyl-2-phenyl-6,7-dihydro-1,2,4-
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The title compound, C 12 H 14 N 6 , was synthesized via cyclocondensation of 5-guanidino-3-phenyl-1,2,4-triazole with acetone. Only one tautomeric form with the NH H atom vicinal to the methyl groups was observed in the crystal structure. The triazine ring adopts a flattened half-boat conformation.