Preparation of 2,4,5-trisubstituted pyrazolo[4,3-c]quinolin-3-ones
✍ Scribed by Douglas C. Beshore; Robert M. DiPardo; Scott D. Kuduk
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- French
- Weight
- 931 KB
- Volume
- 51
- Category
- Article
- ISSN
- 0040-4039
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📜 SIMILAR VOLUMES
## Abstract 4‐Hydroxy‐3‐arylhydrazonoalkyl‐2‐quinolones 6 or reactive derivatives such as 3‐arylhydrazonoalkyl‐4‐tosyloxy‐2‐quinolones **7** or 4‐chloro‐3‐arylhydrazonoalkyl‐2‐quinolones **14**, which are obtained __via__ 3‐acyl‐4‐hydroxyquinolones **4, 10** or 3‐phenylarrmomethylene‐quinoline‐2,4‐
## Abstract The new pyrazolo[4,3‐__c__]quinolin‐3‐one derivatives 3a‐c and 6a‐c were prepared by the following three steps: first the preparation of ethyl 4‐hydroxyquinoline‐3‐carboxylate derivatives 1 and 4 by reaction of isatoic anhydrides and ethyl malonate and ethyl acetoacetate respectively, t
## Synthesis of New Pyrazolo[4, quinolin-3-ones Derivatives and Some Oxazolo[4,5-c]quinoline-2,4-diones. -With a view to obtaining new drugs, the title compounds, which can be structurally compared to analogous compounds of known immunomodulatory activity, are prepared. -(ISMAILI,