## Abstract A method is described for small‐scale laboratory simulation of the industrial process for the manufacture of guazatine, an agrochemical fungicide comprising a mixture of guanidated di‐, tri‐, and poly‐amines derived from octamethylenediamine. The product has been prepared with carbon‐14
Preparation of 14C-labelled poly(ℓ-menthyl isopropenyl carbonates)
✍ Scribed by Roger A. Comes; Harvey J. Grubbs
- Publisher
- John Wiley and Sons
- Year
- 1981
- Tongue
- French
- Weight
- 275 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0022-2135
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✦ Synopsis
Abstract
The synthesis of ^14^C‐labelled poly(ℓ‐menthyl isopropenyl carbonate) is described. Experimental conditions are included for incorporation of ^14^C into each of the carbon atoms in the molecule. High pressure liquid chromatography conditions are given for separation and purification of the labelled intermediates.
📜 SIMILAR VOLUMES
## Abstract 1‐[^14^C]‐__α__‐Aminopropanephosphonic acid, with a specific activity of 1.736 µCi mg^−1^, has been prepared from 1‐[^14^C]‐propanal, triphenyl phosphite, and benzyl carbamate by interaction in toluene in the presence of boron trifluoride‐etherate, followed by hydrolysis. The product wa
Nitration of N-ethoxy~arbonyl-[U-~~C]aniline with two equivalents of nitric acid in sulfuric acid afforded N-ethoxycarbonyl-2,4-dinitro-[U-l4C]aniline which was deprotected quantitatively to P,Cdinitro-[U-l4C]aniline. Selective hydrogenation provided 99.5% radiochemically pure [U-I 4C]nitrophenylene
The sulfonamide potentiator ormetoprim (6) has been prepared with a carbon-14 label for use in biolo ical studies. The key intermediate, 2-methylveratraldehyde (4, was prepared by 14CO2 carbonation of the Grignard reagent from 2-bromo-4,5dimethoxytaluene (1) followed by esterification, reduction an