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Preparation, characterization, and in vivo evaluation of doxorubicin loaded BSA nanoparticles with folic acid modified dextran surface

โœ Scribed by Hao, Hequn; Ma, Qingming; Huang, Chong; He, Fen; Yao, Ping


Book ID
120664699
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
851 KB
Volume
444
Category
Article
ISSN
0378-5173

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To reduce the toxicity of methotrexate (MTX) and increase the targeting of nanoparticles, the MTX-loaded chitosan (CS) covalently bonded with folic acid (FA) nanoparticles were prepared, and sodium tripolyphosphate was used as the cross-linking agent. FA was successfully conjugated to CS confirmed b