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Preparation and some reactions of 9-(disubstituted amino)-9H-pyrrolo[1,2-a]indoles

✍ Scribed by Raines, Stephen; Chai, Sie Yearl; Palopoll, Frank P.


Book ID
126870676
Publisher
American Chemical Society
Year
1971
Tongue
English
Weight
286 KB
Volume
36
Category
Article
ISSN
0022-3263

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πŸ“œ SIMILAR VOLUMES


Synthetic studies on substituted 9h-pyrr
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## Mitomycin antibiotics (I) have a novel ring system that is aziridinopyrrolo II 1,2-a indoloquinone(1). In synthetic studies on mitomycin analogs Lederle group synthesised 7-benzyloxy-9H-pyrrolo 1,2-a indole(2) and substituted 2,3r.

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## Abstract A novel method is reported for the synthesis of 9,9‐disubstituted 9__H__‐pyrrolo[1,2‐__a__]indoles. Cyclization of 1‐[2‐(1‐aryl(or methyl)ethenyl)phenyl]‐1__H__‐pyrroles, which can be easily prepared from 2‐(1‐aryl(or methyl)ethenyl)anilines, proceeds smoothly, in general, at 0Β° in the

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## Abstract The novel method is performed in the presence of either a catalytic or stoichiometric amount of HI.