Preparation and evaluation of novel chiral stationary phases covalently bound with chiral pseudo-18-crown-6 ethers
✍ Scribed by Keiji Hirose; Takashi Nakamura; Ryota Nishioka; Tetsuro Ueshige; Yoshito Tobe
- Book ID
- 104252973
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- French
- Weight
- 92 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
Novel chiral stationary phases consisting of silica gel covalently bound with chiral pseudo-18-crown-6 type hosts, which possess either an OH or OMe group as a binding functionality, were prepared for enantiomer-separation of lipophilic amines.
📜 SIMILAR VOLUMES
## Abstract A novel chiral stationary phase based on chitosan covalently bonded onto silica gels has been prepared and used for the separation of various α‐amino acid enantiomers as well as α‐hydroxycarboxylic acid enantiomers by chiral ligand‐exchange chromatography with copper(II) as a complexing
A crown ether-based chiral stationary phase (CSP) without extra aminopropyl groups on the surface of silica gel was newly prepared by bonding (+)-(18-crown-6)-2,3,11,12-tetracarboxylic acid to silica gel. The new CSP was applied to the resolution of various racemic alpha-amino acids, amines, and ami