Synthesis and characterization of chitos
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Mohammad Reza Saboktakin; Roya M. Tabatabaie; Abel Maharramov; Mohammad Ali Rama
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Article
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2010
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John Wiley and Sons
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English
β 149 KB
The main aim of this research was to develop and evaluate a multiparticulate system of Ac-poly(amidoamine)(PAMAM)(G4)-chitosan (CS) hydrogels exploiting pH-sensitive and specific biodegradability properties for colon-targeted delivery of 5-aminosalicylic acid (5-ASA). All formulations were evaluated