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Preparation and evaluation of magnetic microspheres of mesalamine (5-aminosalicylic acid) for colon drug delivery

✍ Scribed by Kakar, Satinder; Batra, Deepa; Singh, Ramandeep


Book ID
121675476
Publisher
Medknow Publications
Year
2013
Tongue
English
Weight
987 KB
Volume
2
Category
Article
ISSN
2221-6189

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The main aim of this research was to develop and evaluate a multiparticulate system of Ac-poly(amidoamine)(PAMAM)(G4)-chitosan (CS) hydrogels exploiting pH-sensitive and specific biodegradability properties for colon-targeted delivery of 5-aminosalicylic acid (5-ASA). All formulations were evaluated