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Preparation and biological evaluation of 18F-labeled benzamide analogs as potential dopamine D2 receptor ligands

✍ Scribed by Kiesewetter, Dale O.; Kawai, Ryosei; Chelliah, Meena; Owens, Ernest; McLellan, Catherine; Blasberg, Ronald G.


Book ID
122749721
Publisher
Elsevier Science
Year
1990
Weight
976 KB
Volume
17
Category
Article
ISSN
0883-2897

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## Abstract This study evaluated the utility of __(S)‐N__‐[(1‐ethyl‐2‐pyrrolidinyl)methyl]‐5‐(3‐[^18^F]fluoropropyl)‐2,3‐dimethoxybenzamide ([^18^F]fluoropropylepidepride), [^18^F]5‐FPrEpid, as a ligar d for PET studies of cerebral dopamine D2 receptors. The in vitro affinity for the rat striatal d