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Preorganization of the Bioactive Conformation of Sialyl LewisX Analogues Correlates with Their Affinity to E-Selectin

โœ Scribed by Gebhard Thoma; John L. Magnani; John T. Patton; Beat Ernst; Wolfgang Jahnke


Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
121 KB
Volume
113
Category
Article
ISSN
0044-8249

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The expression of E-selectin receptors on the surface of endothelial cells stimulated by cytokines i s one of the first steps in inflammatory processes.[" E-selectin i s a membrane-resident ylycoprotein belonging to the selectin family (E-selectin. L-selectin, P-selectin) which specifically binds th