Thirty cases of fungating breast cancer (stages 111 and IV) were treated preoperatively by combination chemotherapy using cyclophosphamide (Endoxan), methotrexate, 5-fluorouracil, and prednisone. Mastectomy was performed after 2 cycles of preoperative chemotherapy followed by 6 more cycles postopera
Preoperative chemotherapy for mesoblastic nephroma
โ Scribed by Chan, K. L. ;Chan, K. W. ;Lee, C. W. ;Saing, Htut
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 245 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0098-1532
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โฆ Synopsis
A neonate with extensive stage I l l mesoblastic nephroma was confirmed at operation to have a tumor that was too infiltrative and too advanced for primary excision. The abdomen was closed after multiple biopsies. Vincristine (1.1 mg/m2) was given intravenously once a week for a total of eight doses. Repeat CT scan confirmed shrinkage of the tumor and a nephrectomy could be per-formed safely and the tumor removed at the second laparotomy. CT scan repeated 1 year later showed no recurrence. This case illustrates the effective use of a single drug pre-excision chemotherapy which allowed a nephrectomy for extensive stage Ill mesoblastic nephroma to be carried out safely.
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