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Preoperative chemotherapy for fungating breast cancer

✍ Scribed by Dr. Anand Kumar; L. L. Shah; Sushila Khanna; N. N. Khanna

Publisher
John Wiley and Sons
Year
1987
Tongue
English
Weight
327 KB
Volume
36
Category
Article
ISSN
0022-4790

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✦ Synopsis

Thirty cases of fungating breast cancer (stages 111 and IV) were treated preoperatively by combination chemotherapy using cyclophosphamide (Endoxan), methotrexate, 5-fluorouracil, and prednisone. Mastectomy was performed after 2 cycles of preoperative chemotherapy followed by 6 more cycles postoperatively. Of 30 patients, 25 (83.3%) were made operable and had better disease-free survival. Preoperative chemotherapy has an advantage as regards improvement in quality and longevity without much toxicity, and provides a better palliation.

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