Neoadjuvant (preoperative) chemotherapy for breast cancer
โ Scribed by Joseph Ragaz; Robert Baird; Patricia Rebbeck; James Goldie; Andrew Coldman; John Spinelli
- Publisher
- John Wiley and Sons
- Year
- 1985
- Tongue
- English
- Weight
- 556 KB
- Volume
- 56
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Thirty cases of fungating breast cancer (stages 111 and IV) were treated preoperatively by combination chemotherapy using cyclophosphamide (Endoxan), methotrexate, 5-fluorouracil, and prednisone. Mastectomy was performed after 2 cycles of preoperative chemotherapy followed by 6 more cycles postopera
## Abstract ## Background Neoadjuvant chemotherapy for breast cancer reduces tumour cellularity, the percentage of the primary tumour area that is composed of invasive tumour cells. Minimal residual tumour cellularity (5 per cent or less of tumour area composed of invasive tumour cells) may be ass
Thirty-eight patients with locally advanced breast cancer (Stage HI) were treated over a 3-year period. All patients initially received two cycles of CMF (cyclophosphamide, 100 mg/m2 p.0. dl-14; methotrexate 40mg/m2 intravenously (iv), d l and d8., 5 Fluorouracil 500 mg/m2 iv d l and d8). They were