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Preliminary immunological studies in spinal muscular atrophy

✍ Scribed by Barbara Ryniewicz; Maria Pawińska

Publisher
Springer
Year
1978
Tongue
English
Weight
215 KB
Volume
128
Category
Article
ISSN
0340-6997

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✦ Synopsis

Evidence of impaired cell-mediated immunity in children with spinal muscular atrophy was obtained using lymphocyte transformation with PHA (20 children) and skin tests with tuberculin and DNCB (35 children). Laryngological examination of 16 children demonstrated hypoplasia of lymphatic tissue in Waldeyer's ring and the cervical lymph nodes. An ectodermal defect involving both spinal cord and thymus is suggested.

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