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Statistical considerations in the study of spinal muscular atrophy

โœ Scribed by C. Ralph Buncher; Frederick Samaha; Susan T. Iannaccone; Barry D. Russman; Jay D. Cook; Michael White; Carolyn McLaughlin


Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
249 KB
Volume
13
Category
Article
ISSN
0148-639X

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## Abstract The hereditary neurodegenerative disease spinal muscular atrophy (SMA) with childhood onset is one of the most common genetic causes of infant mortality. The disease is characterized by selective loss of spinal cord motor neurons leading to muscle atrophy and is the result of mutations