Pregnancy in a patient with homozygous familial hypercholesterolemia undergoing low-density lipoprotein apheresis by dextran sulfate adsorption
✍ Scribed by J.L. Teruel; M.A. Lasunción; J.F. Navarro; P. Carrero; J. Ortuño
- Book ID
- 116031379
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 512 KB
- Volume
- 44
- Category
- Article
- ISSN
- 1532-8600
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A novel on-line system for the selective precipitation of low-density lipoprotein (LDL) using dextran sulfate has been devised and tested in four patients with heterozygous familial hypercholesterolemia (type 11). The mean pretreatment serum cholesterol was 410 mg/dl. Plasma was generated by membran
Removal of low-density lipoproteins from plasma by dextran sulfate adsorption (DSA) in FH patients entails a decrease in plasma levels of thyroid hormones (-28.5% and -18.78, respectively, for T3 and T4). This suggests that FH patients have a greater than normal fraction of thyroid hormones bound to