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Decrease of thyroid hormones in patients with familial hypercholesterolemia during dextran sulphate low-density lipoprotein apheresis

โœ Scribed by S. Pintus; Dr. P. Pintus; C. Piras; A. Loviselli; S. Muntoni


Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
187 KB
Volume
9
Category
Article
ISSN
0733-2459

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โœฆ Synopsis


Removal of low-density lipoproteins from plasma by dextran sulfate adsorption (DSA) in FH patients entails a decrease in plasma levels of thyroid hormones (-28.5% and -18.78, respectively, for T3 and T4). This suggests that FH patients have a greater than normal fraction of thyroid hormones bound to lipoproteins, due to their expanded lipoprotein pool.


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Reduction of low-density lipoproteins wi
โœ G. Delbert Antwiler; Peter C. Dau; Donn D. Lobdell ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 822 KB

A novel on-line system for the selective precipitation of low-density lipoprotein (LDL) using dextran sulfate has been devised and tested in four patients with heterozygous familial hypercholesterolemia (type 11). The mean pretreatment serum cholesterol was 410 mg/dl. Plasma was generated by membran