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Predictive value of p16ink4a and p53 alterations for the prognosis of resected early stage non-small cell lung cancer

✍ Scribed by J. Niklinski; W. Niklinska; L. Chyczewski; G. Lapuc; J. Laudanski


Book ID
117658291
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
167 KB
Volume
37
Category
Article
ISSN
0959-8049

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The p p ! 6INK4 and p I8 genes are members of the gene famil coding for inhibitors of cyclin-dependent kinases 4 and 6. frequently deleted in many human neoplasms. To examine the role of these 3 genes in lung carcinogenesis, somatic mutations within the genes were analyzed by single-strand conformat