Expression of p16INK4a/p16α and p19ARF/p16β is frequently altered in non-small cell lung cancer and correlates with p53 overexpression
✍ Scribed by Vonlanthen, Silvia; Heighway, Jim; Tschan, Mario P; Borner, Markus M; Altermatt, Hans J; Kappeler, Andreas; Tobler, Andreas; Fey, Martin F; Thatcher, Nick; Yarbrough, Wendell G
- Book ID
- 110061949
- Publisher
- Nature Publishing Group
- Year
- 1998
- Tongue
- English
- Weight
- 470 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0950-9232
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
The p p ! 6INK4 and p I8 genes are members of the gene famil coding for inhibitors of cyclin-dependent kinases 4 and 6. frequently deleted in many human neoplasms. To examine the role of these 3 genes in lung carcinogenesis, somatic mutations within the genes were analyzed by single-strand conformat
Primary cultured mouse hepatic cells become senescent within a short period, although rare cells form colonies from which continuously proliferating cell lines can be established. In contrast, hepatic tumor (HT) cells show little senescence and higher colony-forming capacity. To assess this differen