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Predictive testing for complex diseases using multiple genes: Fact or fiction?

โœ Scribed by Janssens, A Cecile J W; Aulchenko, Yurii S; Elefante, Stefano; Borsboom, Gerard J J M; Steyerberg, Ewout W; van Duijn, Cornelia M


Book ID
120639813
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
411 KB
Volume
8
Category
Article
ISSN
1098-3600

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Genome scanning for complex disease gene
โœ Dr. Tara Cox Matise ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 294 KB

Two tests for allelic association were applied to a simulated complex disease for the Genetic Analysis Workshop 9. The transmission/disequilibrium test [Spielman et al., 19931 and the haplotype-based haplotype relative risk approach [Terwilliger and Ott, 19921 were used to detect disease-associated