Prediction of response to chemotherapy by ERCC1 immunohistochemistry and ERCC1 polymorphism in ovarian cancer
✍ Scribed by K.D. STEFFENSEN; M. WALDSTRØM; U. JEPPESEN; I. BRANDSLUND; A. JAKOBSEN
- Book ID
- 109086270
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 469 KB
- Volume
- 18
- Category
- Article
- ISSN
- 1048-891X
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Our purpose is to evaluate the predictive value of the genetic polymorphisms of Excision repair cross-complementing group 1 (ERCC1) and xeroderma pigmentosum group D/excision repair crosscomplementing group 2 (XPD/ERCC2) in patients with advanced colorectal cancer receiving oxaliplatin-based chemoth
## Abstract This study compares __Br__east __Ca__ncer 1 (__BRCA1__) and excision repair cross complementation group 1 (__ERCC1__) expression as predictive markers and evaluates the __in vitro__ enhancement of platinum sensitivity using targeted agents in sporadic ovarian cancer (OC). A retrospectiv