Prediction of response of acute nonlymphocytic leukaemia to therapy with ‘high dose’ cytosine arabinoside
✍ Scribed by H. D. Preisler; J. Epstein; M. Barcos; R. Priore; A. Raza; G. P. Browman; R. Vogler; E. Winton; H. Grunwald; K. Rai; J. Brennan; J. Bennett; J. Goldberg; A. Gottlieb; P. Chervenick; R. Joyce; K. Miller; R. Larson; P. D'Arrigo; T. Doeblin; M. Stein; M. Bloom; R. Steele; H. Lee
- Book ID
- 114710302
- Publisher
- John Wiley and Sons
- Year
- 1984
- Tongue
- English
- Weight
- 781 KB
- Volume
- 58
- Category
- Article
- ISSN
- 0007-1048
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High dose cytosine arabinoside (HD-AraC) was evaluated 1) as remission induction therapy for refractory acute leukemia and high risk AML, 2) as augmentation therapy for acute leukemia, and 3) as conditioning therapy prior to allogeneic bone marrow transplantation for acute leukemia. Seven of 10 pati
Effective treatment of the elderly patients (265 years) with acute nonlymphocytic leukemia (ANLL) remains elusive and controversial. In the present study, single-agent Cytosine Arabinoside (AM-C) was administered at an intermediate dose level (500 mg/m2 intravenously [I.V.] I-hour infusion q12 hours