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Prediction of DNA-binding specificity in zinc finger proteins

โœ Scribed by Roy, Sumedha; Dutta, Shayoni; Khanna, Kanika; Singla, Shruti; Sundar, Durai


Book ID
113094066
Publisher
Indian Academy of Sciences
Year
2012
Tongue
English
Weight
193 KB
Volume
37
Category
Article
ISSN
0250-5991

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Artificial transcription factors based on modified zinc-finger DNA-binding domains have been shown to activate or repress the transcription of endogenous genes in multiple organisms. Advances in both the construction of novel zinc-finger proteins and our understanding of the characteristics of a pro