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Preclinical Evaluation of Antiviral Compounds in the SCID-hu Mouse

✍ Scribed by J. McCUNE; H. KANESHIMA; L. RABIN; C.-C. SHIH; R. NAMIKAWA

Book ID
119864118
Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
400 KB
Volume
616
Category
Article
ISSN
0890-6564

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Fifteen percent of all human melanomas carry mutations in ras genes, the majority of which are located in codon 61 of the N-ras gene. However, the biological significance of these mutations is as yet unknown. In this study, we investigated the influence of N-ras oncogene products mutated in codon 61