𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Use of hu-IgG-SCID mice to evaluate the in vivo stability of human monoclonal IgG antibodies

✍ Scribed by Renée Bazin; Gérard Boucher; Guy Monier; Marie-Claire Chevrier; Sylvain Verrette; Hervé Broly; Réal Lemieux


Book ID
118902986
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
665 KB
Volume
172
Category
Article
ISSN
0022-1759

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Contribution of variable domains to the
✍ Roxana M. Ionescu; Josef Vlasak; Colleen Price; Marc Kirchmeier 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 354 KB

Temperature-induced unfolding of three humanized IgG1 monoclonal antibodies and their Fab and Fc fragments was monitored by differential scanning calorimetry at neutral pH. With some exceptions, the thermogram of the intact antibody presents two peaks and the transition with the larger experimental

Identification of peptides that bind to
✍ George K. Ehrlich; Pascal Bailon 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 98 KB 👁 2 views

The pFc' fragments of a humanized IgG 1 monoclonal antibody were generated by digestion with immobilized pepsin. These pFc' fragments were separated from F(ab') 2 fragments by affinity chromatography. The pFc' fragments corresponding to the constant region of the humanized IgG 1 monoclonal antibody