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Therapeutic evaluation of compounds in the SCID-RA papillomavirus model

✍ Scribed by David C Lobe; John W Kreider; William C Phelps


Book ID
114145180
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
713 KB
Volume
40
Category
Article
ISSN
0166-3542

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Fifteen percent of all human melanomas carry mutations in ras genes, the majority of which are located in codon 61 of the N-ras gene. However, the biological significance of these mutations is as yet unknown. In this study, we investigated the influence of N-ras oncogene products mutated in codon 61