Practical Routes to 2,6-Disubstituted Pyridine Derivatives
✍ Scribed by Lucie Vandromme; Hans-Ulrich Reißig; Susie Gröper; Jürgen P. Rabe
- Book ID
- 102171229
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 254 KB
- Volume
- 2008
- Category
- Article
- ISSN
- 1434-193X
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📜 SIMILAR VOLUMES
A regiospecific synthesis of 2,6-disubstituted pyridines and HT, H20 (R' = H) (vi) AcOH, boil (R' = AC). We have previously attempted to prepare 7-bromotriazolopyridine by treatment of the 7-lithio derivative (1) with bromine at -40 "C but even at this low temperature ring opening was so rapid that
The synthesis of (S)-2-methyl tetrahydropyridine-N-oxide (4), a key intermediate for the enantioselective construction of trans-2,6-disubsdtuted piperidines via [3+2] nitrone cycloaddition reaction, is described. Nitrone 4 was elaborated to the fire ant venom alkaloid (+)-solenopsin-A (2) via interm