Synthesis of 4-(2-diphenylphosphino-1-na
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V Gautheron Chapoulaud; J Audoux; N Plé; A Turck; G Quéguiner
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Article
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1999
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Elsevier Science
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French
⚖ 168 KB
We describe a multistep synthesis leading in a good yield to the title compound. The biaryl linkage was formed in a Pd-catalysed coupling of 2-phenyl-4-chloroquinazoline with 2-methoxy-l-naphthylboronic acid. A further metal-catalysed reaction gave the formation of the naphthylphosphorus bond allowi