Several dominant genetic diseases which appear to be homogeneous are the expression of genetic mutations at several loci. The power to detect linkage by likelihood methods is diminished for heterogeneous, as compared to genetically homogeneous, disorders. Using a simulation approach and two pedigree
Power of Neutrality Tests to Detect Bottlenecks and Hitchhiking
β Scribed by Frantz Depaulis; Sylvain Mousset; Michel Veuille
- Publisher
- Springer
- Year
- 2003
- Tongue
- English
- Weight
- 236 KB
- Volume
- 57
- Category
- Article
- ISSN
- 0022-2844
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