Several dominant genetic diseases which appear to be homogeneous are the expression of genetic mutations at several loci. The power to detect linkage by likelihood methods is diminished for heterogeneous, as compared to genetically homogeneous, disorders. Using a simulation approach and two pedigree
Power of a chromosomal test to detect genetic variation using genetic markers
✍ Scribed by VISSCHER*†; HALEY ‡
- Publisher
- Nature Publishing Group
- Year
- 1998
- Tongue
- English
- Weight
- 958 KB
- Volume
- 81
- Category
- Article
- ISSN
- 0018-067X
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