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Potential Use of Polyamidoamine Dendrimer Conjugates with Cyclodextrins as Novel Carriers for siRNA

✍ Scribed by Arima, Hidetoshi; Motoyama, Keiichi; Higashi, Taishi


Book ID
118057785
Publisher
MDPI AG
Year
2011
Tongue
English
Weight
572 KB
Volume
5
Category
Article
ISSN
1424-8247

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Potential use of polyamidoamine dendrime
✍ Toshihito Tsutsumi; Fumitoshi Hirayama; Kaneto Uekama; Hidetoshi Arima πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 677 KB

The potential of starburst 1 polyamidoamine dendrimer (dendrimer, generation 3, G3) conjugate with a-cyclodextrin (a-CyD) having an average degree of substitution of 2.4 (a-CDE) as a novel carrier of short hairpin RNA (shRNA) expressing plasmid DNA (shpDNA) was evaluated and the shpDNA transfer acti