Potential Use of Dendrimer/α-Cyclodextrin Conjugate as a Novel Carrier for Small Interfering RNA (siRNA)

Potential use of polyamidoamine dendrime

Potential use of polyamidoamine dendrimer/α-cyclodextrin conjugate (generation 3, G3) as a novel carrier for short hairpin RNA-expressing plasmid DNA

✍ Toshihito Tsutsumi; Fumitoshi Hirayama; Kaneto Uekama; Hidetoshi Arima 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 677 KB

The potential of starburst 1 polyamidoamine dendrimer (dendrimer, generation 3, G3) conjugate with a-cyclodextrin (a-CyD) having an average degree of substitution of 2.4 (a-CDE) as a novel carrier of short hairpin RNA (shRNA) expressing plasmid DNA (shpDNA) was evaluated and the shpDNA transfer acti