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Evaluation of polyamidoamine dendrimer/α-cyclodextrin conjugate (generation 3, G3) as a novel carrier for small interfering RNA (siRNA)

✍ Scribed by Toshihito Tsutsumi; Fumitoshi Hirayama; Kaneto Uekama; Hidetoshi Arima


Book ID
113691529
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
862 KB
Volume
119
Category
Article
ISSN
0168-3659

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Potential use of polyamidoamine dendrime
✍ Toshihito Tsutsumi; Fumitoshi Hirayama; Kaneto Uekama; Hidetoshi Arima 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 677 KB

The potential of starburst 1 polyamidoamine dendrimer (dendrimer, generation 3, G3) conjugate with a-cyclodextrin (a-CyD) having an average degree of substitution of 2.4 (a-CDE) as a novel carrier of short hairpin RNA (shRNA) expressing plasmid DNA (shpDNA) was evaluated and the shpDNA transfer acti