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Potential role of endothelin-1 and endothelin antagonists in cardiovascular diseases

✍ Scribed by Simone Schmitz-Spanke; J. D. Schipke


Publisher
Springer
Year
2000
Tongue
English
Weight
185 KB
Volume
95
Category
Article
ISSN
0300-8428

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Endothelin-1 is mainly synthesized by the vascular endothelial cells and acts on the vascular smooth muscle. Because of its vasoconstrictor and mitogenic effects it plays a role in the development of vascular diseases. In diabetes mellitus atherosclerosis is accelerated. The authors summarize the av